MovDisordV3, France, Analysis, bibRecord, 000178

Depression comorbidity in spinocerebellar ataxia

Identifieur interne : 000178 ( France/Analysis ); précédent : 000177; suivant : 000179

Depression comorbidity in spinocerebellar ataxia

Auteurs : Tanja Schmitz-Hübsch [Allemagne] ; Mathieu Coudert [France] ; Sophie Tezenas Du Montcel [France] ; Paola Giunti [Royaume-Uni] ; Robyn Labrum [Royaume-Uni] ; Alexandra Dürr [France] ; Pascale Ribai [France] ; Perrine Charles [France] ; Christoph Linnemann [Allemagne] ; Ludger Schöls [Allemagne] ; Maryla Rakowicz [Pologne] ; Rafal Rola [Pologne] ; Elszbieta Zdzienicka [Pologne] ; Roberto Fancellu [Italie] ; Caterina Mariotti [Italie] ; Lazlo Baliko [Hongrie] ; Bela Melegh [Hongrie] ; Alessandro Filla [Italie] ; Elena Salvatore [Italie] ; Bart P. C. Van De Warrenburg [Pays-Bas] ; Sandra Szymanski [Allemagne] ; Jon Infante [Espagne] ; Dagmar Timmann [Allemagne] ; Sylvia Boesch [Autriche] ; Chantal Depondt [Belgique] ; Jun-Suk Kang [Allemagne] ; Jörg B. Schulz [Allemagne] ; Thomas Klopstock [Allemagne] ; Nicole Lossnitzer [Allemagne] ; Bernd Löwe [Allemagne] ; Caroline Frick [Allemagne] ; Daniela Rottl Nder [Allemagne] ; Thomas E. Schlaepfer [Allemagne, États-Unis] ; Thomas Klockgether [Allemagne]

Source :

Movement Disorders [ 0885-3185 ] ; 2011-04.

RBID : ISTEX:50B77A4B4C970763DCD1BFCBA3F272B70C8B5985

English descriptors

KwdEn :
- Aged, Antidepressive Agents (therapeutic use), Comorbidity, Depression (drug therapy), Depression (epidemiology), Female, Humans, Male, Middle Aged, Prevalence, Spinocerebellar Ataxias (epidemiology), Spinocerebellar Ataxias (genetics), cerebellum, depression, prevalence studies, spinocerebellar ataxia.
MESH :
- chemical , therapeutic use : Antidepressive Agents.
- drug therapy : Depression.
- epidemiology : Depression, Spinocerebellar Ataxias.
- genetics : Spinocerebellar Ataxias.
- Aged, Comorbidity, Female, Humans, Male, Middle Aged, Prevalence.

Abstract

This is a description of the prevalence and profile of depressive symptoms in dominant spinocerebellar ataxia (SCA). Depressive symptoms were assessed in a convenience sample of 526 genetically confirmed and clinically affected patients (117 SCA1, 163 SCA2, 139 SCA3, and 107 SCA6) using the Patient Health Questionnaire (PHQ). In addition, depressive status according to the examiner and the use of antidepressants was recorded. Depression self‐assessment was compared with an interview‐based psychiatric assessment in a subset of 26 patients. Depression prevalence estimates were 17.1% according to the PHQ algorithm and 15.4% when assessed clinically. The sensitivity of clinical impression compared with PHQ classification was low (0.35), whereas diagnostic accuracy of PHQ compared with psychiatric interview in the subset was high. Antidepressants were used by 17.7% of patients and in >10% of patients without current clinically relevant depressive symptoms. Depression profile in SCA did not differ from a sample of patients with major depressive disorder except for the movement‐related item. Neither depression prevalence nor use of antidepressants differed between genetic subtypes, with only sleep disturbance more common in SCA3. In a multivariate analysis, ataxia severity and female sex independently predicted depressive status in SCA. The PHQ algorithmic classification is appropriate for use in SCA but should stimulate further psychiatric evaluation if depression is indicated. Despite a higher risk for depression with more severe disease, the relation of depressive symptoms to SCA neurodegeneration remains to be shown. © 2011 Movement Disorder Society

Url:

https://api.istex.fr/document/50B77A4B4C970763DCD1BFCBA3F272B70C8B5985/fulltext/pdf

DOI: 10.1002/mds.23698

Affiliations:

Links to Exploration step

ISTEX:50B77A4B4C970763DCD1BFCBA3F272B70C8B5985

Le document en format XML

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<author><name sortKey="Tezenas Du Montcel, Sophie" sort="Tezenas Du Montcel, Sophie" uniqKey="Tezenas Du Montcel S" first="Sophie" last="Tezenas Du Montcel">Sophie Tezenas Du Montcel</name>
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<author><name sortKey="Labrum, Robyn" sort="Labrum, Robyn" uniqKey="Labrum R" first="Robyn" last="Labrum">Robyn Labrum</name>
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<wicri:regionArea>Division of Neurogenetics, National Hospital of Neurology and Neurosurgery, Queen Square, London</wicri:regionArea>
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<author><name sortKey="Durr, Alexandra" sort="Durr, Alexandra" uniqKey="Durr A" first="Alexandra" last="Dürr">Alexandra Dürr</name>
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<affiliation wicri:level="1"><country xml:lang="fr">France</country>
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<placeName><settlement type="city">Paris</settlement>
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<author><name sortKey="Ribai, Pascale" sort="Ribai, Pascale" uniqKey="Ribai P" first="Pascale" last="Ribai">Pascale Ribai</name>
<affiliation wicri:level="1"><country xml:lang="fr">France</country>
<wicri:regionArea>INSERM, UMR_S679 Neurologie & Thérapeutique Expérimentale, Paris</wicri:regionArea>
<placeName><settlement type="city">Paris</settlement>
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<affiliation wicri:level="1"><country xml:lang="fr">France</country>
<wicri:regionArea>AP‐HP, Hôpital de la Salpêtrière, Department of Genetics and Cytogenetics, Paris</wicri:regionArea>
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<author><name sortKey="Charles, Perrine" sort="Charles, Perrine" uniqKey="Charles P" first="Perrine" last="Charles">Perrine Charles</name>
<affiliation wicri:level="1"><country xml:lang="fr">France</country>
<wicri:regionArea>INSERM, UMR_S679 Neurologie & Thérapeutique Expérimentale, Paris</wicri:regionArea>
<placeName><settlement type="city">Paris</settlement>
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<affiliation wicri:level="1"><country xml:lang="fr">France</country>
<wicri:regionArea>AP‐HP, Hôpital de la Salpêtrière, Department of Genetics and Cytogenetics, Paris</wicri:regionArea>
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<author><name sortKey="Linnemann, Christoph" sort="Linnemann, Christoph" uniqKey="Linnemann C" first="Christoph" last="Linnemann">Christoph Linnemann</name>
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<region type="district" nuts="2">District de Tübingen</region>
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<author><name sortKey="Schols, Ludger" sort="Schols, Ludger" uniqKey="Schols L" first="Ludger" last="Schöls">Ludger Schöls</name>
<affiliation wicri:level="3"><country xml:lang="fr">Allemagne</country>
<wicri:regionArea>Department of Neurology and Hertie‐Institute for Clinical Brain Research, University of Tübingen, Tübingen</wicri:regionArea>
<placeName><region type="land" nuts="1">Bade-Wurtemberg</region>
<region type="district" nuts="2">District de Tübingen</region>
<settlement type="city">Tübingen</settlement>
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<author><name sortKey="Rakowicz, Maryla" sort="Rakowicz, Maryla" uniqKey="Rakowicz M" first="Maryla" last="Rakowicz">Maryla Rakowicz</name>
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<wicri:regionArea>Department of Clinical Neurophysiology, Institute of Psychiatry and Neurology, Warsaw</wicri:regionArea>
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<author><name sortKey="Rola, Rafal" sort="Rola, Rafal" uniqKey="Rola R" first="Rafal" last="Rola">Rafal Rola</name>
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<wicri:regionArea>First Department of Neurology, Institute of Psychiatry and Neurology, Warsaw</wicri:regionArea>
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<author><name sortKey="Zdzienicka, Elszbieta" sort="Zdzienicka, Elszbieta" uniqKey="Zdzienicka E" first="Elszbieta" last="Zdzienicka">Elszbieta Zdzienicka</name>
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<wicri:regionArea>Department of Genetics, Institute of Psychiatry and Neurology, Warsaw</wicri:regionArea>
<wicri:noRegion>Warsaw</wicri:noRegion>
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</author>
<author><name sortKey="Fancellu, Roberto" sort="Fancellu, Roberto" uniqKey="Fancellu R" first="Roberto" last="Fancellu">Roberto Fancellu</name>
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<wicri:regionArea>Department of Biochemistry and Genetics, Fondazione‐IRCCS, Istituto Neurologico Carlo Besta, Milan</wicri:regionArea>
<placeName><settlement type="city">Milan</settlement>
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</affiliation>
</author>
<author><name sortKey="Mariotti, Caterina" sort="Mariotti, Caterina" uniqKey="Mariotti C" first="Caterina" last="Mariotti">Caterina Mariotti</name>
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<wicri:regionArea>Department of Biochemistry and Genetics, Fondazione‐IRCCS, Istituto Neurologico Carlo Besta, Milan</wicri:regionArea>
<placeName><settlement type="city">Milan</settlement>
<region nuts="2">Lombardie</region>
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</affiliation>
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<author><name sortKey="Baliko, Lazlo" sort="Baliko, Lazlo" uniqKey="Baliko L" first="Lazlo" last="Baliko">Lazlo Baliko</name>
<affiliation wicri:level="1"><country xml:lang="fr">Hongrie</country>
<wicri:regionArea>Department of Neurology and Stroke, County Hospital, Veszprém</wicri:regionArea>
<wicri:noRegion>Veszprém</wicri:noRegion>
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</author>
<author><name sortKey="Melegh, Bela" sort="Melegh, Bela" uniqKey="Melegh B" first="Bela" last="Melegh">Bela Melegh</name>
<affiliation wicri:level="1"><country xml:lang="fr">Hongrie</country>
<wicri:regionArea>Department of Medical Genetics and Child Development, University of Pécs</wicri:regionArea>
<wicri:noRegion>University of Pécs</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Filla, Alessandro" sort="Filla, Alessandro" uniqKey="Filla A" first="Alessandro" last="Filla">Alessandro Filla</name>
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<wicri:regionArea>Department of Neurology, University of Naples, Naples</wicri:regionArea>
<wicri:noRegion>Naples</wicri:noRegion>
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</author>
<author><name sortKey="Salvatore, Elena" sort="Salvatore, Elena" uniqKey="Salvatore E" first="Elena" last="Salvatore">Elena Salvatore</name>
<affiliation wicri:level="1"><country xml:lang="fr">Italie</country>
<wicri:regionArea>Department of Neurology, University of Naples, Naples</wicri:regionArea>
<wicri:noRegion>Naples</wicri:noRegion>
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<author><name sortKey="Van De Warrenburg, Bart P C" sort="Van De Warrenburg, Bart P C" uniqKey="Van De Warrenburg B" first="Bart P. C." last="Van De Warrenburg">Bart P. C. Van De Warrenburg</name>
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<wicri:regionArea>Department of Neurology, Donders Centre for Neuroscience, Radboud University Nijmegen Medical Center, Nijmegen</wicri:regionArea>
<placeName><settlement type="city">Nimègue</settlement>
<region type="province" nuts="2">Gueldre</region>
</placeName>
</affiliation>
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<author><name sortKey="Szymanski, Sandra" sort="Szymanski, Sandra" uniqKey="Szymanski S" first="Sandra" last="Szymanski">Sandra Szymanski</name>
<affiliation wicri:level="1"><country xml:lang="fr">Allemagne</country>
<wicri:regionArea>Department of Neurology, St. Josef Hospital, University Hospital of Bochum, Bochum</wicri:regionArea>
<wicri:noRegion>Bochum</wicri:noRegion>
<wicri:noRegion>Bochum</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Infante, Jon" sort="Infante, Jon" uniqKey="Infante J" first="Jon" last="Infante">Jon Infante</name>
<affiliation wicri:level="1"><country xml:lang="fr">Espagne</country>
<wicri:regionArea>Department of Neurology, University Hospital “Marqués de Valdecilla,” CIBERNED, Santander</wicri:regionArea>
<wicri:noRegion>Santander</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Timmann, Dagmar" sort="Timmann, Dagmar" uniqKey="Timmann D" first="Dagmar" last="Timmann">Dagmar Timmann</name>
<affiliation wicri:level="1"><country xml:lang="fr">Allemagne</country>
<wicri:regionArea>Department of Neurology, University Hospital of Essen, Essen</wicri:regionArea>
<wicri:noRegion>Essen</wicri:noRegion>
<wicri:noRegion>Essen</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Boesch, Sylvia" sort="Boesch, Sylvia" uniqKey="Boesch S" first="Sylvia" last="Boesch">Sylvia Boesch</name>
<affiliation wicri:level="1"><country xml:lang="fr">Autriche</country>
<wicri:regionArea>Department of Neurology, University of Innsbruck, Innsbruck</wicri:regionArea>
<wicri:noRegion>Innsbruck</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Depondt, Chantal" sort="Depondt, Chantal" uniqKey="Depondt C" first="Chantal" last="Depondt">Chantal Depondt</name>
<affiliation wicri:level="4"><country xml:lang="fr">Belgique</country>
<wicri:regionArea>Department of Neurology, Hôpital Erasme, Université Libre de Bruxelles, Brussels</wicri:regionArea>
<placeName><settlement type="city">Bruxelles</settlement>
<region nuts="2">Région de Bruxelles-Capitale</region>
</placeName>
<orgName type="university">Université libre de Bruxelles</orgName>
</affiliation>
</author>
<author><name sortKey="Kang, Jun Uk" sort="Kang, Jun Uk" uniqKey="Kang J" first="Jun-Suk" last="Kang">Jun-Suk Kang</name>
<affiliation wicri:level="1"><country xml:lang="fr">Allemagne</country>
<wicri:regionArea>Department of Neurology, University of Frankfurt, Frankfurt/M</wicri:regionArea>
<wicri:noRegion>Frankfurt/M</wicri:noRegion>
<wicri:noRegion>Frankfurt/M</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Schulz, Jorg B" sort="Schulz, Jorg B" uniqKey="Schulz J" first="Jörg B." last="Schulz">Jörg B. Schulz</name>
<affiliation wicri:level="3"><country xml:lang="fr">Allemagne</country>
<wicri:regionArea>Department of Neurology, University Clinic, RTHW Aachen, Aachen</wicri:regionArea>
<placeName><region type="land" nuts="1">Rhénanie-du-Nord-Westphalie</region>
<region type="district" nuts="2">District de Cologne</region>
<settlement type="city">Aix-la-Chapelle</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Klopstock, Thomas" sort="Klopstock, Thomas" uniqKey="Klopstock T" first="Thomas" last="Klopstock">Thomas Klopstock</name>
<affiliation wicri:level="3"><country xml:lang="fr">Allemagne</country>
<wicri:regionArea>Department of Neurology, Friedrich‐Baur‐Institute, University Hospital of Ludwig‐Maximilians‐University, München</wicri:regionArea>
<placeName><region type="land" nuts="1">Bavière</region>
<region type="district" nuts="2">District de Haute-Bavière</region>
<settlement type="city">Munich</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Lossnitzer, Nicole" sort="Lossnitzer, Nicole" uniqKey="Lossnitzer N" first="Nicole" last="Lossnitzer">Nicole Lossnitzer</name>
<affiliation wicri:level="3"><country xml:lang="fr">Allemagne</country>
<wicri:regionArea>Department of Psychosomatic and General Internal Medicine, Medical University Hospital Heidelberg, Heidelberg</wicri:regionArea>
<placeName><region type="land" nuts="1">Bade-Wurtemberg</region>
<region type="district" nuts="2">District de Karlsruhe</region>
<settlement type="city">Heidelberg</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Lowe, Bernd" sort="Lowe, Bernd" uniqKey="Lowe B" first="Bernd" last="Löwe">Bernd Löwe</name>
<affiliation wicri:level="3"><country xml:lang="fr">Allemagne</country>
<wicri:regionArea>Department of Psychosomatic Medicine and Psychotherapy, University Medical Center Hamburg‐Eppendorf and Hamburg‐Eilbek (Schön Clinics), Hamburg</wicri:regionArea>
<placeName><settlement type="city">Hambourg</settlement>
<region type="land" nuts="2">Hambourg</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Frick, Caroline" sort="Frick, Caroline" uniqKey="Frick C" first="Caroline" last="Frick">Caroline Frick</name>
<affiliation wicri:level="3"><country xml:lang="fr">Allemagne</country>
<wicri:regionArea>Department of Psychiatry and Psychotherapy, University Clinic Bonn, Bonn</wicri:regionArea>
<placeName><region type="land" nuts="1">Rhénanie-du-Nord-Westphalie</region>
<region type="district" nuts="2">District de Cologne</region>
<settlement type="city">Bonn</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Rottl Nder, Daniela" sort="Rottl Nder, Daniela" uniqKey="Rottl Nder D" first="Daniela" last="Rottl Nder">Daniela Rottl Nder</name>
<affiliation wicri:level="3"><country xml:lang="fr">Allemagne</country>
<wicri:regionArea>Department of Psychiatry and Psychotherapy, University Clinic Bonn, Bonn</wicri:regionArea>
<placeName><region type="land" nuts="1">Rhénanie-du-Nord-Westphalie</region>
<region type="district" nuts="2">District de Cologne</region>
<settlement type="city">Bonn</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Schlaepfer, Thomas E" sort="Schlaepfer, Thomas E" uniqKey="Schlaepfer T" first="Thomas E." last="Schlaepfer">Thomas E. Schlaepfer</name>
<affiliation wicri:level="3"><country xml:lang="fr">Allemagne</country>
<wicri:regionArea>Department of Psychiatry and Psychotherapy, University Clinic Bonn, Bonn</wicri:regionArea>
<placeName><region type="land" nuts="1">Rhénanie-du-Nord-Westphalie</region>
<region type="district" nuts="2">District de Cologne</region>
<settlement type="city">Bonn</settlement>
</placeName>
</affiliation>
<affiliation wicri:level="2"><country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Department of Psychiatry and Behavioral Science, Johns Hopkins University, Baltimore, Maryland</wicri:regionArea>
<placeName><region type="state">Maryland</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Klockgether, Thomas" sort="Klockgether, Thomas" uniqKey="Klockgether T" first="Thomas" last="Klockgether">Thomas Klockgether</name>
<affiliation wicri:level="3"><country xml:lang="fr">Allemagne</country>
<wicri:regionArea>Department of Neurology, University Hospital of Bonn, Bonn</wicri:regionArea>
<placeName><region type="land" nuts="1">Rhénanie-du-Nord-Westphalie</region>
<region type="district" nuts="2">District de Cologne</region>
<settlement type="city">Bonn</settlement>
</placeName>
</affiliation>
</author>
</analytic>
<monogr></monogr>
<series><title level="j">Movement Disorders</title>
<title level="j" type="abbrev">Mov. Disord.</title>
<idno type="ISSN">0885-3185</idno>
<idno type="eISSN">1531-8257</idno>
<imprint><publisher>Wiley Subscription Services, Inc., A Wiley Company</publisher>
<pubPlace>Hoboken</pubPlace>
<date type="published" when="2011-04">2011-04</date>
<biblScope unit="vol">26</biblScope>
<biblScope unit="issue">5</biblScope>
<biblScope unit="page" from="870">870</biblScope>
<biblScope unit="page" to="876">876</biblScope>
</imprint>
<idno type="ISSN">0885-3185</idno>
</series>
<idno type="istex">50B77A4B4C970763DCD1BFCBA3F272B70C8B5985</idno>
<idno type="DOI">10.1002/mds.23698</idno>
<idno type="ArticleID">MDS23698</idno>
</biblStruct>
</sourceDesc>
<seriesStmt><idno type="ISSN">0885-3185</idno>
</seriesStmt>
</fileDesc>
<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Aged</term>
<term>Antidepressive Agents (therapeutic use)</term>
<term>Comorbidity</term>
<term>Depression (drug therapy)</term>
<term>Depression (epidemiology)</term>
<term>Female</term>
<term>Humans</term>
<term>Male</term>
<term>Middle Aged</term>
<term>Prevalence</term>
<term>Spinocerebellar Ataxias (epidemiology)</term>
<term>Spinocerebellar Ataxias (genetics)</term>
<term>cerebellum</term>
<term>depression</term>
<term>prevalence studies</term>
<term>spinocerebellar ataxia</term>
</keywords>
<keywords scheme="MESH" type="chemical" qualifier="therapeutic use" xml:lang="en"><term>Antidepressive Agents</term>
</keywords>
<keywords scheme="MESH" qualifier="drug therapy" xml:lang="en"><term>Depression</term>
</keywords>
<keywords scheme="MESH" qualifier="epidemiology" xml:lang="en"><term>Depression</term>
<term>Spinocerebellar Ataxias</term>
</keywords>
<keywords scheme="MESH" qualifier="genetics" xml:lang="en"><term>Spinocerebellar Ataxias</term>
</keywords>
<keywords scheme="MESH" xml:lang="en"><term>Aged</term>
<term>Comorbidity</term>
<term>Female</term>
<term>Humans</term>
<term>Male</term>
<term>Middle Aged</term>
<term>Prevalence</term>
</keywords>
</textClass>
<langUsage><language ident="en">en</language>
</langUsage>
</profileDesc>
</teiHeader>
<front><div type="abstract" xml:lang="en">This is a description of the prevalence and profile of depressive symptoms in dominant spinocerebellar ataxia (SCA). Depressive symptoms were assessed in a convenience sample of 526 genetically confirmed and clinically affected patients (117 SCA1, 163 SCA2, 139 SCA3, and 107 SCA6) using the Patient Health Questionnaire (PHQ). In addition, depressive status according to the examiner and the use of antidepressants was recorded. Depression self‐assessment was compared with an interview‐based psychiatric assessment in a subset of 26 patients. Depression prevalence estimates were 17.1% according to the PHQ algorithm and 15.4% when assessed clinically. The sensitivity of clinical impression compared with PHQ classification was low (0.35), whereas diagnostic accuracy of PHQ compared with psychiatric interview in the subset was high. Antidepressants were used by 17.7% of patients and in >10% of patients without current clinically relevant depressive symptoms. Depression profile in SCA did not differ from a sample of patients with major depressive disorder except for the movement‐related item. Neither depression prevalence nor use of antidepressants differed between genetic subtypes, with only sleep disturbance more common in SCA3. In a multivariate analysis, ataxia severity and female sex independently predicted depressive status in SCA. The PHQ algorithmic classification is appropriate for use in SCA but should stimulate further psychiatric evaluation if depression is indicated. Despite a higher risk for depression with more severe disease, the relation of depressive symptoms to SCA neurodegeneration remains to be shown. © 2011 Movement Disorder Society</div>
</front>
</TEI>
<affiliations><list><country><li>Allemagne</li>
<li>Autriche</li>
<li>Belgique</li>
<li>Espagne</li>
<li>France</li>
<li>Hongrie</li>
<li>Italie</li>
<li>Pays-Bas</li>
<li>Pologne</li>
<li>Royaume-Uni</li>
<li>États-Unis</li>
</country>
<region><li>Angleterre</li>
<li>Bade-Wurtemberg</li>
<li>Bavière</li>
<li>District de Cologne</li>
<li>District de Haute-Bavière</li>
<li>District de Karlsruhe</li>
<li>District de Tübingen</li>
<li>Grand Londres</li>
<li>Gueldre</li>
<li>Hambourg</li>
<li>Lombardie</li>
<li>Maryland</li>
<li>Rhénanie-du-Nord-Westphalie</li>
<li>Région de Bruxelles-Capitale</li>
</region>
<settlement><li>Aix-la-Chapelle</li>
<li>Bonn</li>
<li>Bruxelles</li>
<li>Hambourg</li>
<li>Heidelberg</li>
<li>Londres</li>
<li>Milan</li>
<li>Munich</li>
<li>Nimègue</li>
<li>Paris</li>
<li>Tübingen</li>
</settlement>
<orgName><li>Université libre de Bruxelles</li>
</orgName>
</list>
<tree><country name="Allemagne"><region name="Rhénanie-du-Nord-Westphalie"><name sortKey="Schmitz Bsch, Tanja" sort="Schmitz Bsch, Tanja" uniqKey="Schmitz Bsch T" first="Tanja" last="Schmitz-Hübsch">Tanja Schmitz-Hübsch</name>
</region>
<name sortKey="Frick, Caroline" sort="Frick, Caroline" uniqKey="Frick C" first="Caroline" last="Frick">Caroline Frick</name>
<name sortKey="Kang, Jun Uk" sort="Kang, Jun Uk" uniqKey="Kang J" first="Jun-Suk" last="Kang">Jun-Suk Kang</name>
<name sortKey="Klockgether, Thomas" sort="Klockgether, Thomas" uniqKey="Klockgether T" first="Thomas" last="Klockgether">Thomas Klockgether</name>
<name sortKey="Klopstock, Thomas" sort="Klopstock, Thomas" uniqKey="Klopstock T" first="Thomas" last="Klopstock">Thomas Klopstock</name>
<name sortKey="Linnemann, Christoph" sort="Linnemann, Christoph" uniqKey="Linnemann C" first="Christoph" last="Linnemann">Christoph Linnemann</name>
<name sortKey="Lossnitzer, Nicole" sort="Lossnitzer, Nicole" uniqKey="Lossnitzer N" first="Nicole" last="Lossnitzer">Nicole Lossnitzer</name>
<name sortKey="Lowe, Bernd" sort="Lowe, Bernd" uniqKey="Lowe B" first="Bernd" last="Löwe">Bernd Löwe</name>
<name sortKey="Rottl Nder, Daniela" sort="Rottl Nder, Daniela" uniqKey="Rottl Nder D" first="Daniela" last="Rottl Nder">Daniela Rottl Nder</name>
<name sortKey="Schlaepfer, Thomas E" sort="Schlaepfer, Thomas E" uniqKey="Schlaepfer T" first="Thomas E." last="Schlaepfer">Thomas E. Schlaepfer</name>
<name sortKey="Schols, Ludger" sort="Schols, Ludger" uniqKey="Schols L" first="Ludger" last="Schöls">Ludger Schöls</name>
<name sortKey="Schulz, Jorg B" sort="Schulz, Jorg B" uniqKey="Schulz J" first="Jörg B." last="Schulz">Jörg B. Schulz</name>
<name sortKey="Szymanski, Sandra" sort="Szymanski, Sandra" uniqKey="Szymanski S" first="Sandra" last="Szymanski">Sandra Szymanski</name>
<name sortKey="Timmann, Dagmar" sort="Timmann, Dagmar" uniqKey="Timmann D" first="Dagmar" last="Timmann">Dagmar Timmann</name>
</country>
<country name="France"><noRegion><name sortKey="Coudert, Mathieu" sort="Coudert, Mathieu" uniqKey="Coudert M" first="Mathieu" last="Coudert">Mathieu Coudert</name>
</noRegion>
<name sortKey="Charles, Perrine" sort="Charles, Perrine" uniqKey="Charles P" first="Perrine" last="Charles">Perrine Charles</name>
<name sortKey="Charles, Perrine" sort="Charles, Perrine" uniqKey="Charles P" first="Perrine" last="Charles">Perrine Charles</name>
<name sortKey="Coudert, Mathieu" sort="Coudert, Mathieu" uniqKey="Coudert M" first="Mathieu" last="Coudert">Mathieu Coudert</name>
<name sortKey="Durr, Alexandra" sort="Durr, Alexandra" uniqKey="Durr A" first="Alexandra" last="Dürr">Alexandra Dürr</name>
<name sortKey="Durr, Alexandra" sort="Durr, Alexandra" uniqKey="Durr A" first="Alexandra" last="Dürr">Alexandra Dürr</name>
<name sortKey="Ribai, Pascale" sort="Ribai, Pascale" uniqKey="Ribai P" first="Pascale" last="Ribai">Pascale Ribai</name>
<name sortKey="Ribai, Pascale" sort="Ribai, Pascale" uniqKey="Ribai P" first="Pascale" last="Ribai">Pascale Ribai</name>
<name sortKey="Tezenas Du Montcel, Sophie" sort="Tezenas Du Montcel, Sophie" uniqKey="Tezenas Du Montcel S" first="Sophie" last="Tezenas Du Montcel">Sophie Tezenas Du Montcel</name>
<name sortKey="Tezenas Du Montcel, Sophie" sort="Tezenas Du Montcel, Sophie" uniqKey="Tezenas Du Montcel S" first="Sophie" last="Tezenas Du Montcel">Sophie Tezenas Du Montcel</name>
</country>
<country name="Royaume-Uni"><region name="Angleterre"><name sortKey="Giunti, Paola" sort="Giunti, Paola" uniqKey="Giunti P" first="Paola" last="Giunti">Paola Giunti</name>
</region>
<name sortKey="Labrum, Robyn" sort="Labrum, Robyn" uniqKey="Labrum R" first="Robyn" last="Labrum">Robyn Labrum</name>
</country>
<country name="Pologne"><noRegion><name sortKey="Rakowicz, Maryla" sort="Rakowicz, Maryla" uniqKey="Rakowicz M" first="Maryla" last="Rakowicz">Maryla Rakowicz</name>
</noRegion>
<name sortKey="Rola, Rafal" sort="Rola, Rafal" uniqKey="Rola R" first="Rafal" last="Rola">Rafal Rola</name>
<name sortKey="Zdzienicka, Elszbieta" sort="Zdzienicka, Elszbieta" uniqKey="Zdzienicka E" first="Elszbieta" last="Zdzienicka">Elszbieta Zdzienicka</name>
</country>
<country name="Italie"><region name="Lombardie"><name sortKey="Fancellu, Roberto" sort="Fancellu, Roberto" uniqKey="Fancellu R" first="Roberto" last="Fancellu">Roberto Fancellu</name>
</region>
<name sortKey="Filla, Alessandro" sort="Filla, Alessandro" uniqKey="Filla A" first="Alessandro" last="Filla">Alessandro Filla</name>
<name sortKey="Mariotti, Caterina" sort="Mariotti, Caterina" uniqKey="Mariotti C" first="Caterina" last="Mariotti">Caterina Mariotti</name>
<name sortKey="Salvatore, Elena" sort="Salvatore, Elena" uniqKey="Salvatore E" first="Elena" last="Salvatore">Elena Salvatore</name>
</country>
<country name="Hongrie"><noRegion><name sortKey="Baliko, Lazlo" sort="Baliko, Lazlo" uniqKey="Baliko L" first="Lazlo" last="Baliko">Lazlo Baliko</name>
</noRegion>
<name sortKey="Melegh, Bela" sort="Melegh, Bela" uniqKey="Melegh B" first="Bela" last="Melegh">Bela Melegh</name>
</country>
<country name="Pays-Bas"><region name="Gueldre"><name sortKey="Van De Warrenburg, Bart P C" sort="Van De Warrenburg, Bart P C" uniqKey="Van De Warrenburg B" first="Bart P. C." last="Van De Warrenburg">Bart P. C. Van De Warrenburg</name>
</region>
</country>
<country name="Espagne"><noRegion><name sortKey="Infante, Jon" sort="Infante, Jon" uniqKey="Infante J" first="Jon" last="Infante">Jon Infante</name>
</noRegion>
</country>
<country name="Autriche"><noRegion><name sortKey="Boesch, Sylvia" sort="Boesch, Sylvia" uniqKey="Boesch S" first="Sylvia" last="Boesch">Sylvia Boesch</name>
</noRegion>
</country>
<country name="Belgique"><region name="Région de Bruxelles-Capitale"><name sortKey="Depondt, Chantal" sort="Depondt, Chantal" uniqKey="Depondt C" first="Chantal" last="Depondt">Chantal Depondt</name>
</region>
</country>
<country name="États-Unis"><region name="Maryland"><name sortKey="Schlaepfer, Thomas E" sort="Schlaepfer, Thomas E" uniqKey="Schlaepfer T" first="Thomas E." last="Schlaepfer">Thomas E. Schlaepfer</name>
</region>
</country>
</tree>
</affiliations>
</record>

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Movement Disorders (revue)

Depression comorbidity in spinocerebellar ataxia

Depression comorbidity in spinocerebellar ataxia

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	Movement Disorders (revue)
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